Vitex agnus-castus
نویسندگان
چکیده
Vitex agnus-castus has a long tradition as a herbal remedy and was used in ancient times not only as an anaphrodisiac and for preserving chastity but also against diverse disturbances of the female genital system. In actual clinical trials, the fruit Agni casti fructus was shown to relieve premenstrual syndrome (PMS) and especially breast swelling and pain, due to its dopaminergic effect. Although approximately 50% or more of young women suffer from PMS, there is no generally accepted therapy and only a few preparations for that purpose are available on the Swiss market. Therefore the extract preparation Ze440 was developed and its effectiveness has been studied in a clinical trial. In a controlled, double blind study 170 women suffering from PMS were treated with Ze440 during three menstrual cycles. 52% of the treated patients had a significant improvement in the combined symptoms, relative to those on placebo (24%). The positive results of the clinical trial show that PMS can successfully be treated with the extract preparation Ze440. Today the product is available in the Swiss market under the brand names Prefemin® and Premens®.
منابع مشابه
Systematic Review of Premenstrual, Postmenstrual and Infertility Disorders of Vitex Agnus Castus
INTRODUCTION Vitex agnus-castus, also called vitex is aboriginal to the Mediterranean region, with long leaves, tender stem, flowers and ripening seeds. The aim of this study was to overview premenstrual, postmenstrual and infertility disorder of Vitex agnus-castus. METHODS This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. Th...
متن کاملComparison of Vitex agnus castus Extract and Pergolide in Treatment of Equine Cushing's Syndrome
Pituitary pars intermedia hyperplasia, which causes Equine Cushing’s Syndrome, has been treated with dopaminergic agonists such as pergolide. Vitex agnus castus (Chaste Berry) extract has been used medicinally for centuries for various human female cycle disorders, and a lay article claimed its therapeutic efficacy in horses with pituitary hyperplasia and other hormonal dysfunction. Ethanol ext...
متن کاملEvaluation of anti-inflammatory activity of Vitex agnus
Vitex agnus-castus L., (Verbenaceae) traditional Chinese medicinal plant recommended for various inflammatory ailments, but its mechanism of anti-inflammatory action is still unclear. The present study reports the anti-inflammatory activities of various extracts and elucidate possible mechanism(s) with the quantification of flavonoids by RP-HPLC. The petroleum ether, ethyl acetate, methanol and...
متن کاملAntiproliferative Effect of Extracts , Fractions and Compound from Vitex rotundifolia on Human Cancer Cells
متن کامل
Can Vitex Agnus Castus be Used for the Treatment of Mastalgia? What is the Current Evidence?
There have been many treatments suggested for the management of mastalgia; one of these is the fruit extract of Vitex Agnus castus L. commonly known as Agnus castus, an extract of a deciduous shrub native to Mediterranean Europe and Central Asia. It is postulated that A. castus suppresses the stress-induced latent hyperprolactinemia which is a release of supra-physiological levels of prolactin ...
متن کاملAlecrim de Angola - Vitex Agnus-castus
Vitex agnus-castus L. (chaste-berry). Phytomedicine. 2004 Jan;11(1):18-23. Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Department of Medicinal Chemistry and Pharmacognosy, UIC/NIH Center for Botanical Dietary Supplements Research, College of Pharmacy, University of Illinois at Chicago, Chicago, Illi...
متن کامل